Figure in Picture 1. What is the rate law for the SN2 reaction in terms of the n

Question

Figure in Picture

1. What is the rate law for the SN2 reaction in terms of the nucleophile and the electrophile?

2. How does the rate of the reaction depend on the nucleophile (Nu:) and on the leaving group (LG:)?

3. How does the structure of the substrate (R-LG) affect the rate of the reaction?

4. Which solvents are best for the SN2 reaction (which ones make it faster by increasing the rate)?

5. Show an example of this reaction.

What is the rate law for the SN2 reaction in terms of the nucleophile and the electrophile? How does the rate of the reaction depend on the nucleophile (Nu:) and on the leaving group (LG:)? How does the structure of the substrate (R-LG) affect the rate of the reaction? Which solvents are best for the SN2 reaction (which ones make it faster by increasing the rate)? Show an example of this reaction.

Explanation / Answer

1) second order, 2) nucleophile should be strong, and better leaving group 3) primary alkyl halide will participate in SN2 reaction, and if stereocentre is present in substrate that configuration will change in product 4) polar aprotic solvents , like DMF, DMSO

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