(a) addition of a high concentration ofa analog of GTP GTP (b) addition of a dru
ID: 79323 • Letter: #
Question
(a) addition of a high concentration ofa analog of GTP GTP (b) addition of a drug that prevents subunit from exchanging GDP the (c) mutations acetylcholine receptor that weaken the interaction between in the receptor and acetylcholine mutations in the acetylcholine receptor that weaken the interaction between the (d) receptor and the G protein 12. Which of the following statements molecular switches is false? turning (a) remove the phosphate from GTP on GTP-binding proteins, them off. (b) Protein kinases transfer the terminal phosphate from ATP onto a protein. (c) Seri kinases are the most common types of protein kinase. (d) A GTP-binding protein exchanges its bound GDP for GTP to become activated 13. During the mating process, yeast cells respond to pheromones secreted by other yeast cells. These pheromones bind GPCRs on the surface of the responding cell and lead to the activation of G proteins inside the cell. When a wild-type yeast cell senses the pheromone, its physiology changes in preparation for mating: the cell stops growing until it finds a mating partner. If yeast cells do not undergo the appropriate response after sensing a pheromone, they are considered sterile. Yeast cells that are defective in one or more components of the G protein have characteristic phenotypes in the absence and presence of the pheromone, which are listed in Table 16-34. phenotype mutation minus pheromone plus pheromone none (wild type) normal growth arrested growth, mating response a subunit deleted arrested growth arrested growth, sterile subunit deleted normal growth normal growth, sterile Ysubunit deleted normal growth normal growth, sterile a and B deleted normal growth normal growth, sterile Ydeleted normal growth normal growth, sterile a and B and deleted normal growth normal growth, sterile Table Q16-34 which of the following models is consistent with the data from the analysis of these mutants? Explain your answer. a activates the mating response but is inhibited when bound to By (a) (b) activates the mating response but is inhibited when bound to a (c) the G protein is inactive; either free a or free By complex is capable of activating the mating response (d) the G protein is active; both free a and free By complex are required to inhibit the mating responseExplanation / Answer
A molecule that can be reversibly shifted between two or more phases is called as molecular switch. Many intracellular signalling proteins act as molecular switches. Proteins can be temporarily converted from inactive form to active form and vice versa. These proteins are either on or off. so, they are called as molecular switches.
Molecular switches are of two types,
In this question, among the four given options, option (b) is false. Phosphate group is removed by phosphatase and not by protein kinase.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.