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The enzymes weaken substrate bonds chemically and/or by mechanically and that io

ID: 80080 • Letter: T

Question

The enzymes weaken substrate bonds chemically and/or by mechanically and that ionic cofactors may participate in substrate activation in the enzyme active site. When analyzing an enzymatic reaction, it is helpful to think in terms of the attacking group in one substrate and its target in the other substrate. For each of the following reactions, name and describe the attacking functional group, the atom which actually makes the nucleophillic attack, the target functional group, and the target atom within that group. For each reaction identity how each substrate is made more reactive and the specific means by which this is accomplished. There will be some similarities and differences in these reactions If any of the specific explanations for a given reaction are unknown, explain any possible answers which are currently under consideration. 5) Peptidyl hydrolase reaction

Explanation / Answer

In peptidal hydrolase reaction the example is peptidal t RNA hydrolase .it is known to cleave the ester bond between peptide and t RNA and thus the t RNA is released.the attacking functional group is esterase and functional target group is ester.

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