Extra Credit Questions from HIV Describe the process that HIV goes through to en

Question

Extra Credit Questions from HIV Describe the process that HIV goes through to enter its target cell. Name the receptors on the target cell and the envelope proteins in HIV that are responsible for this process (M-tropic/T-tropic). List four cell types that are known target for the HIV virus. Name three enzymes that are packaged within the HIV viral capsid and the role each plays in the viral cycle. List and describe the current and potential types (not brands) of drugs for the treatment of HIV infections.

Explanation / Answer

The HIV virus binds with the receptors on the cell (CD4 Receptor), and Chemokine coreceptor. It fuses with the cell and enters the internal environment of the cell. The HIV is uncoated inside the cell. The retrotranscription takes place and HIV provirus is imported in the nucleus. The integration of the cellular DNA and HIV provirus takes place. This leads to the transactivation of target gene and LTR.

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