8. In order to find out whether the use of oral contraceptives affects the risk
ID: 81140 • Letter: 8
Question
8. In order to find out whether the use of oral contraceptives affects the risk of developing in myocardial infarction (MI), a trol study was carried out among married nurses the United States, where 159 case-cont cases infarction were compared with oral hospitalized of the controls used controls. The results showed that 21 the cases and 273 of contraceptives. measure of effect of oral a. Name, compute, and interpret the appropriate contraceptives on MI risk. [2 points] b. Describe the general criteria for confounding and identify one specific confounder that should be considered in this study. points]Explanation / Answer
8a) The oral contraceptive drugs reduce the chances of developing myocardial infarction, arteriosclerosis as it was revealed in experiments on mice that the lipoproteins levels like HDL,LDL, were low after taking oral contraceptive drugs.
b)general criteria for confounding in statistics study on a group of nurses who developed myocardial infarction after taking oral contraceptives was due to excessive hypertension and stress due to work load, and smoking and alcohol intake in women. Further case study of glucose tolerance levels and diabetes in these nurses is an indication of myocardial infarction. The blood pressure gets lowered after intake of oral contraceptive drugs.
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