4a. In a population of Lesser Snozzlewompins, a species of horned rodent that th

Question

4a. In a population of Lesser Snozzlewompins, a species of horned rodent that thrives on the high elevation plains of the Andean Plateau, allele H of the horn size gene mutates to allele h at a rate of 1 copy per 100 alleles, per generation. In other words, for every 100 H alleles made during gamete formation, 1 will be converted to an h allele by mutation. If the initial allele frequencies are H = 0.7 and h = 0.3, what are the expected allele frequencies in the next generation, assuming all other conditions of the Hardy-Weinberg principle are being satisfied? Please show all of your work and calculations. 4b. Next, let's assume that the population of Lesser Snozzlewompins is reduced in size to the degree that genetic drift becomes a significant mechanism of allele frequency change. Using the mutation rate you calculated above, determine the effective population size (Ne) required to offset the effects of genetic drift.

Explanation / Answer

Initial frequencies

H=0.7 , h=0.3

And for every 100 alleles 1 allele is mutated

That means for every 100 H, 1 is converted into h

In that rate the allelic frequencies also changes in the following manner

Allelic frequency H becomes------- H - 1% of H

0.7 - 1% of 0.7

=0.693

If H has became 0.693 , then h will become 0. 307

So the changed allelic frequencies are H = 0.693

and h=0.307.

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