please give explaination and answer At your job as a genetic counselor, your cli
ID: 82696 • Letter: P
Question
please give explaination and answer
At your job as a genetic counselor, your client is a distraught young woman. She explains to you that her mother has blood type A, her father has blood type AB, and she has blood type O. She has been told that this is not genetically possible. Your initial suspicion in this case is that there was infidelity (i.e. her father is not really her father), but the young woman refuses to accept this explanation. For her sake, you agree to investigate other possibilities. Your assignment in this project therefore is to determine if there is a logical genetic explanation for this scenario, or if infidelity must be concluded. In formulating your answer, be sure to include explanations of how multiple alleles and epistasis affect inheritance patterns.
Explanation / Answer
The term multiple allele is used to describe when the trait is controlled by more than two alleles. Blood type is the most common example of this as it does have three alleles, specifically "A", "B", and "O" blood types. Each of these controls the production of different antigenic substances on the surface of red blood cells. Both A and B are dominant, in the case of AB blood type codominance occurs and type O blood is recessive.
The Bombay blood type occurs when an individual is homozygous for a genetic variant encoding a defective enzyme. These individuals cannot produce the glycoprotein precursor required for A and B blood type enzymes, and appear type O regardless of genotype at the ABO locus. This is an example of epistasis. The presence of H antigen influences the expression of A and B antigens.
The presence of bombay blood type could be a possible explanation for having a blood type O with parents having blood type A and blood type AB.
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