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The use of performance-enhancing drug is illegal in Olympic and other internatio

ID: 828548 • Letter: T

Question

The use of performance-enhancing drug is illegal in Olympic and other international competitions. Many sport governing bodies require athletes to undergo random drug tests, involving blood or urine analysis. How would you analyse a urine sample for drugs and drug metabolites? Remember that there are a wide variety of drug ( everything from alkanes to highly-conjugated molecules with multiple functional groups), but the list of compounds is finite and known ( ie. you are testing for specific organic molecules)



Give specific details on experimental parameters and comment on sample preparation. {instrument: such as GC, IR, electrophoresis, MS etc, details on detection , sample prep, quantitation}

Explanation / Answer

http://www.shimadzu.com/an/industry/pharmaceuticallifescience/metabolism0301020.htm

http://www.shimadzu.com/an/industry/pharmaceuticallifescience/0301015metabolism.htm

http://www.wikihow.com/Pass-a-Urine-Drug-Test