Given reactants and reaction conditions, predict the products of the following t
ID: 835648 • Letter: G
Question
Given reactants and reaction conditions, predict the products of the following types of reactions used to form alcohols. In each case, be able to give the stereochemistry of the product
nucleophilic substitution of alkyl halides
acid-catalyzed hydration of alkenes
oxymercuration-demercuration of alkenes
hydroboration-oxidation of alkenes
hydrolysis of epoxides to form anti vicinal diols (anti hydroxylation of alkenes)
syn hydroxylation of alkenes
synthesis of Grignard reagents & alkyl lithium reagents and addition of these
organometallic reagents to formaldehyde, aldehydes, ketones, esters, acid chlorides, and
epoxides
reduction of carbonyl compounds
Explanation / Answer
1.Nu:- + R--X---------> R--Nu + X-
OH- + R-Cl -------->R-OH + Cl-
2.Acid catalyzed hydration of alkenes is one method of generating alcohols. Regioselectivity of hydration follows Markovnikov's rule in that the hydrogen adds to the carbon with the most hydrogens. Carbocation rearrangement can occur during the reaction.Alcohol+ water is formed
3.The reaction follows Markovnikov's rule .Alcohol+ water is formed
4.the hydroboration
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