Which of the following could occur if a mouse was missing the Xic on each of the

Question

Which of the following could occur if a mouse was missing the Xic on each of the X chromosomes but has an Xic on one copy of chromosome 5?

Question 23 options:

Both of the X chromosomes would express Xist and Tsix.

Chromosome 5 would be compacted to form a Barr body.

Both of the X chromosomes would be compacted to form Barr bodies.

Both copies of the X chromosome would contain Xces.

No Barr bodies would form in the mouse cells.

A)

Both of the X chromosomes would express Xist and Tsix.

B)

Chromosome 5 would be compacted to form a Barr body.

C)

Both of the X chromosomes would be compacted to form Barr bodies.

D)

Both copies of the X chromosome would contain Xces.

E)

No Barr bodies would form in the mouse cells.

Explanation / Answer

Answer- B Option.

Explaination- The X-inactivation center (or simply XIC) on the X chromosome is mandatory for cause X-inactivation. Chromosomal translocations which place the XIC on an autosome (such as chromosome 5,Inthis case) lead to inactivation of the autosome, and X chromosomes lacking the XIC are not inactivated.

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