The resting potential of a neuron is always between -60 and -80 mV. Explain whic

Question

The resting potential of a neuron is always between -60 and -80 mV. Explain which ions play a role in the maintenance of the resting potential, what their concentrations are inside and outside of the neuron (mention equilibrium constants for each) and how their gradients are maintained. Also, discuss how the potential is kept stable between -60 and -80 mV with respect to the ions you have talked about. Na^+ k^+ are the most that changes. Na/k are respond to the resting potential in the cell. Which is call the neuron. The Na/k pump. The pump sent out 3 Na^+ ion out from the cell and sent in 2k^+ in the cell. The membrane has k^+ channel. You artificially depolarize the membrane to reach threshold in an axon midway between the axon hillock and synaptic terminals. Explain how the action potential would along the axon in this artificial setting and why. Suppose a mutation caused a gated sodium channels to remain inactivated long after an action potential. How would this affect the frequency at which action would be generated? Explain what events of an action potential would be affected by this mutation. (Continue on back if you need more space) The action potential propagation occur in one direction because the recently depolarize area of the membrane, absolute refactory an cannot generate an potential action.

Explanation / Answer

1. The membrane potential is the voltage difference resulting in inner and outer parts of the plasma membrane. This depends on activities present in cells, like as sodium and potassium channels with specific channels for transport. Membrane potential is generated due to the different ions content inside and outside the cell and it is linked to adenosine triphosphate (ATP) formation. Three sodium and two potassium gets exchanged and maintains the stability of resting potential.

2. The mutation causes the increase in permeability, despite the membrane potential is clamped, the permeability decays back to its initial level. This is known as inactivation, in which Na+ channels continued in the process of depolarization, which causes repolarization of the action potential.

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