_________ increases drug solubility, giving better absorption A) Phosphodiestera
ID: 84120 • Letter: #
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_________ increases drug solubility, giving better absorption A) Phosphodiesterase B) Prophylactic C) Pyrimidine D) Pegylation The 1906 FDA Law established? A) GMP B) Clinical Trials C) Purity Standards D) Pharmacokinetics A DNA is used for ______ A) approval of a biologic drug B) approval of generic drug C) black box warning D) Orphan Drug Act In order for a pharmaceutical company to rationally design the chemical compound they need to know the _______ of the cellular target A) 3D structure B) Dose scheduling C) Pharmaceyology D) Pegylation When were False claims about drugs outlawed by the FDA? A) 1962 Kefauver-Harris Amendments B) 1938 Federal Food, Drug & Cosmetic Act C) 1927, Bureau of Chemistry changed to the Food, Drug & Insecticide administration D) 1862, started as a single chemist in the USDA High through put screening relies on _________ so a robot can read if the drug has desired action A) Animals B) Quantifiable Assays C) Prophase compound D) None of the above When were Good Manufacturing Practices Established? A) 1962 Kefauver-Harris Amendments B) 1938 Federal Food, Drug & Cosmetic Act C) 1927, Bureau of Chemistry changed to the Food, Drug & Insecticide administration D) 1862, started as a single chemist in the USDAExplanation / Answer
15) D Pegylation - when attached covalently or non covalently to drug molecule, it helps the drug in many ways like mask the drug hence protect the drug from immune system attack, increase the size in solution therefore retains in circulartory system for more time and also increases the drug solubility
16) Purity standards (Standards of purity for food)
17) I think it should be ANDA instead of ADNA.
ANDA- Abbreviated New Drug Application - it is meant for generic drugs hence answer is B
18) 3D structure, Any drug before design, it is important to see how it interacts with the cellular target. And interaction can only be done in precise manner if 3D of cellular target is known.
19) B -1938 federal food, drug and cosmetic act
20) Quantifiable assays
21) 1962 Kefauver-Harris Amendments
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