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Which of the following would most accurately describe the state of a sarcomere i

ID: 84234 • Letter: W

Question

Which of the following would most accurately describe the state of a sarcomere if myosin were mutated such that it had a much higher affinity for ADP but a normal affinity for Pi? The myosin head group would not be engaged in a cross to the thin filament, and it would be in a low-energy conformation. The myosin head will be engaged in a cross-bridge to the thin filament but prior to the power stroke. Most of the myosin heads will be bound to the thin filament after the power stroke but will be unable to release the thin filament. The myosin head group would not be engaged in a cross to the thin filament, and it would be in a high-energy conformation.

Explanation / Answer

Correct answer would be:

The myosin head will be engaged in a cross bridge to the thin filament but prior to the power stroke.

Reason:Prior to the occurence of power stroke ,the myosin will form a cross bridge with actin.

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