You are a graduate student in the lab of a famous fly geneticist. You need to an
ID: 84342 • Letter: Y
Question
You are a graduate student in the lab of a famous fly geneticist. You need to analyze a batch of mutant flies that were recently created in her laboratory to identify the single gene that is most likely mutated in each of the flies.
Drag the mutations on the left to the appropriate blanks on the right to complete the sentences.
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hunchback (a gap gene)
even-skipped (a pair-rule gene)
wingless (a segment-polarity gene)
knirps (a gap gene)
hedgehog (a segment-polarity gene)
Kruppel (a gap gene)
1. The wings are missing in mutant fly L, which is likely the result of a mutation in________ .
2. Mutant fly X has lost the head and thorax. The gene most likely responsible for this mutation is____________.
3. Thoracic and abdominal structures are missing in mutant fly Q. The gene most likely responsible for this mutation is__________ .
4. Mutant fly F has predominantly lost abdominal structures, which is likely the result of a mutation in _________ .
5. The mutation observed in mutant fly O resulted in defects within the anterior or posterior regions of each segment. The gene that most likely caused this mutation is _________.
6. Segment-sized sections of every other segment are missing in mutant fly Z. One likely candidate gene is ________ .
Explanation / Answer
1. Wingless (A segment polarity gene)
2. Hunchback ( A gap gene)
3. Evenskipped ( A pair rule gene)
4. Kruppel (A gap gene)
5. Hedgehog (A segment polarity gene)
6. Knirps (A gap gene).
Segment polarity genes help to define the anterior and posterior polarities within each embryonic parasegment by regulating the transmission of signals.
A gap gene is a type of gene involved in the development of the segmented embryos.
A pair-rule gene is also involved in the development of the segmented embryos. Pair-rule genes are expressed as a result of differing concentrations of gap gene proteins, which encode transcription factors controlling pair-rule gene expression
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