The human blood antigen system has three alleles (A, B, and O). Consider two Add
ID: 8486 • Letter: T
Question
The human blood antigen system has three alleles (A, B, and O). Consider two Additional blood polymorphisms that are also part of the system: two alleles LM and LM determine the M, N, and MN blood groups. The dominant allele 'R' of a different gene causes a person to have the Rh' (rhesus positive) phenotype, whereas the homozygote for 'r' is Rh (rhesus negative). Two men are involved in a paternity dispute, one married to the mother of the children, the other a local Cable TV installer. Each claims all four children as their own. The blood groups for the two men, the another, and each child are as follows: From this evidence, can paternity be established for each of the children? State your conclusions and rationale with respect to each child.Explanation / Answer
assume th
Mother genotype-------------AA,OR AO,-------MN -------RhD+ RhD+, OR RhD+ RhD-,
Husband---------------OO---------------MM------------- RhD+ RhD+,0R RhD+ RhD-,
CABLE Guy ----------------AB---------------------MN---------NEGATIVE RhD- RhD-,
A0 Mother X OO Husband
O
O
A
AO
A -----BLOOD GROUP
AO
A -----BLOOD GROUP
O
OO
O -----BLOOD GROUP
OO
O -----BLOOD GROUP
MN Mother X MM Husband
M
M
M
MM
MM
N
MN
MN
RhD+ RhD-, Mother X RhD+ RhD+, Husband
RhD+
RhD
RhD+
RhD+ RhD+
RhD+ RhD
RhD+
RhD+ RhD+
RhD+ RhD
CHILD
FATHER
EXPLANATION
CHILD 1
FATHER
A0 Mother X OO Husband
CHILD 2
FATHER
A0 Mother X OO Husband
CHILD 3
FATHER
A0 Mother X OO Husband
RhD+ RhD- xRhD+ RhD-
CHILD 3
CABLE Guy
BECASUE OF B BLOOD ,MOTHER AND HUSSBAD DOSENT CARRY THE B ALLELE
the genotypes
Mother genotype-------------AA,OR AO,-------MN ------ RhD+ RhD-
Husband---------------OO---------------MM------------- RhD+ RhD-
O
O
A
AO
A -----BLOOD GROUP
AO
A -----BLOOD GROUP
O
OO
O -----BLOOD GROUP
OO
O -----BLOOD GROUP
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