o 9/30/2014 1 1 :55 PM 40.6/100 Gradebook Print Calculator-Periodic Table Questi

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o 9/30/2014 1 1 :55 PM 40.6/100 Gradebook Print Calculator-Periodic Table Question 4 of 9 Map Answer the following four questions about supercoiling and linking number: a) What is the linking number, Lk, for a relaxed, closed-circular DNA with 3675 base pairs? Enter your answer as an integer Number Lk= b) What is Lk for negatively supercoiled 3675 bp DNA if it is underwound by 2 complete turns? Number Lk= c) How does Lk change when there is a break in one strand? It increases by1 O It is undefined O It decreases by the number of turns removed from the molecule. O It decreases by the number of strands broken. d) What is Lk for negatively supercoiled 3675 bp DNA after treatment with one molecule of topoisomerase lI (DNA gyrase) and adequate ATP? Number Previous Give Up& View Solution Check Answer NextExit Hint

Explanation / Answer

a) 353.365

b) 351.365

c) It decreases by number of turns removed from the molecule

d) 353.365

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