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_Which of the following is an epigenetic mechanism that (almost) always results

ID: 85165 • Letter: #

Question

_Which of the following is an epigenetic mechanism that (almost) always results in gene silencing?

            a. Histone acetylation

            b. CpG methylation

            c. Histone methylation

            d. Chromatin remodeling

_You have identified a Type 2 transposable element in yeast. This transposon has a small mutation, which changes one, but not both, of its inverted repeat sequences. If you provide this transposon with an external source of transposase (as with a Ds element placed near to an Ac element), would you expect this transposon to be able to move?

a. Yes (YES is the correct answer, but I need detailed explanation)

b. No

-You are studying a collection of five biosynthetic mutants in the Vulcan moldlike organism Spockospera (gluck1 – gluck5). All five mutants will grow on minimal medium supplemented with gluck. Two of the mutants, gluck1 and gluck3, will grow in medium supplemented with either gluck or muck. Two of the mutants, gluck2 and gluck5, will grow in medium supplemented with gluck, muck, OR ick. The final mutant, gluck4, requires gluck (none of the other compounds can substitute).

If the order of intermediates in the pathway is as shown below, for which reaction must the product of gluck1 be required?

Precursor                   ick                  muck              gluck

                ------------->         ----------->           ----------->

a. to convert the precursor to ick

b. to convert ick to muck

c. to convert muck to gluck

-

RNA polymerases are required for transcription; however, mutations in one or more of the three eukaryotic RNA polymerases would be

expected to have an effect on translation of all mRNAs, as well. Which RNA polymerase(s), when mutated, would result in the disruption

of protein translation? (Note the difference between disrupting translation and simply not having a message to transcribe in the first

place. I’m asking about the former.)

RNA polymerase I

RNA polymerase II

RNA polymerase III

RNA polymerases I and III

Explanation / Answer

RNA polymeraser II

To convert muck to gluck

No. The transposone can't move by external thing applied on it.