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Please read carefully! Thanks! Ion channels, such as the K^+ channel, can have o

ID: 852354 • Letter: P

Question

Please read carefully! Thanks!

Ion channels, such as the K^+ channel, can have open and closed forms that respond to membrane potential. In addition, an amino-terminal domain, called the inactivation domain or inactivation gate. can block the channel. This is called the ball and chain model of channel inactivation. Identify the statements that correctly describe the ball and chain model. There is more than one true statement. Select all that apply. The inactivation gate can only inactivate a channel that has dosed in response to depolarization. After depolarization and channel opening, the inactivation gate soon occludes the open channel. A mutation causing the loss of the inactivation gate in K^+ channels could result in a membrane that undergoes repolarization more slowly. A shorter tether or chain peptide strand attached to the inactivation domain would increase the time required to inactivate the K^+ channel.

Explanation / Answer

2 and 3

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