These questions will explore the probability of children inheriting a dominant d

Question

These questions will explore the probability of children inheriting a dominant disorder from their parents. a. If the disorder is dominant to being normal and we use the letter "A" for allele symbols, what allele is "A"? What allele is "a"? b. What is the probability that a child will inherit a dominant disorder if one parent is homozygous for the trait and the other is normal? c. What is the probability that a child will inherit a dominant disorder if both parents are homozygous for the trait? d. Assign gene symbols and determine the genotype of the individuals in this pedigree. How can you tell that this pedigree is following a dominant trait? e. Challenge! What is the probability that the individual at the end of the pointer is heterozygous? These questions will explore the probability of children inheriting a recessive disorder from their parents. a. If the disorder is recessive to being normal and we use the letter "A" for allele symbols, what allele is "A"? What allele is "a"?

Explanation / Answer

3. A). A is the dominant allele and 'a' is the recessive allele.

B). If one of the parent has AA genotype and the other has Aa genotype , then out of the four offsprings 2 will have AA and two will have Aa genotypes. Therefore the probability of a child inheriting the disease is 50%.

C). If both the parents are homozygous for the trait, then there is a 100% probability that the child will inherit a dominant disorder.

E). None. The probability of the individual being heterozygous is zero as the individual is affected and thus has to be homozygous in order to be so.

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