There are three \"ketone\" bodies -- acetoacetate, 3-hydroxybutyrate, and aceton

Question

There are three "ketone" bodies -- acetoacetate, 3-hydroxybutyrate, and acetone.

Which of the following is true about ketone bodies?

A. One of them (3-hydroxybutyrate) is not a ketone (!)

B. Acetone production is non-enzymatic; that is, acetone is formed by spontaneous decarboxylation of acetoacetate.

C. These can be considered to be water-soluble fuel sources (sources of acetyl groups).

D. Acetoacetate is synthesized from 2 acetylCoA; and 2 acetylCoA can be obtained, metabolically, from acetoacetate.

E. All of the above are true.

Explanation / Answer

D. Acetoacetate is synthesized from 2 acetylCoA; and 2 acetylCoA can be obtained, metabolically, from acetoacetate.

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