(1.) Need help drawing a mechanism for each step (2) a step by step explanation
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(1.) Need help drawing a mechanism for each step
(2) a step by step explanation of the mechanism and what is each chemical used for to study for a test
Add 1.5 g of thiamine hydrochloride (vitamin B1) and dissolve it in 2 mL of deionized water in a 50 mL Erlenmeyer flask by swirling. Project 6 from "Experimental Organic Chemistry" by J.R. Mohrig, et. al.; W.H. Freeman and Company 1998. Add 15 mL of 95% ethanol and swirl the solution until it is homogeneous. Add to this solution 4.5 mL of an aqueous solution of NaOH (prepared by instructor-40 g of NaOH in 500 mL of di-water), and swirl until bright yellow color fade to a pale yellow color. Add 4.5 ml of benzaldehyde to the flask swirl the contents until homogeneous and stopper. Allow the reaction to take place until next lab period. In a 100 ml round bottom flask, add 0.10 g cupric acetate monohydrate (MW 199.5, 0.5 mmol) and 2.5 g ammonium nitrate (MW 80.0, 31 mmol) to 23 ml of 80% aqueous acetic acid (made from 4.5 ml of water and 18 ml of acetic acid, mixed before adding the other reagents to the flask). Add 5.0 g benzoin (MW 212.2, 24 mmol) in one portion. Fit the flask with a reflux condenser. Reflux mixture (Nitrogen gas is liberated during the course of the redox reaction) and monitor reaction with TLC (CH2CI2 eluent). Compare reaction mixture to benzoin and benzil standard solutions provided by instructor at the beginning, then after approximately 20 min., 40 min., and 60 min. reaction time. Place 1.0 g of benzil and 0.48 g of urea in a 50 mL rb-flask. Add 25 mL of 95% ethanol, and swirl the mixture to dissolve the solids. Add 2.8 mL of 9.4 M KOH (aq) solution, and heat under reflux for 2h. Cool the mixture. If the reaction flask contains a precipitate, vacuum filter to remove from the product solution. Transfer product solution to 150 mL beaker and add 75 mL of water. Add 10% HCl(aq) solution dropwise until pH drops to 4-5 using pH paper indicator. The product will precipitate as the solution is neutralized In the first step of this synthesis, benzaldehyde is converted to benzoin by a condensation reaction that is biochemically catalyzed by thiamine hydrochlorde (vitamin Bl). This reaction is classically catalyzed by the cyanide anion. The environmental benefits of the thiamine-catalyzed version of this reaction areExplanation / Answer
Step 1: Benzaldehyde was reacted to form Benzoin
Step 2: Benzoin undergoes oxidation to form Benzil
Step 3: Benzil was reacted with Urea under basic condition to form 5,5-diphenylhydantoin
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