B. inheritance must be studied by careful analysis of the transmission of partic

Question

B. inheritance must be studied by careful analysis of the transmission of particular be through several generations of a family. Furthermore, the inheritance of the trait the studied in many families 3 and 4 are two human pedigrees, each showing transmission ofa different trait on these pedigrees, circles represent females and squares represent males. Shaded circles and squares are u represent those individuals who have a particular trait. Analyze the pedigrees in Figures 3 and 4 and answer questions 2 3 4 5 6 7 8 9 10 11 12 13 Figure 3. A family history study showing the transmission of a trait through three generations. Copyright o Pearson Custom Publishing

Explanation / Answer

(1)

If figure 3 is carefully observed, it is depicted that males and females are equally affected. It may not be a sex-linked gene, as partial influence on offsprings pertaining to gender is not seen.

(2)

It is an autosomal gene. The male and female offsprings tend to be affected with an equal frequency and no generation is seemed to be unaffected.
Hence, the trait follows autosomal dominant inheritance.

(3)

The gene is dominant one as skipping generations is not seen. It seems all the generations are affected. Hence, it is dominantly inherited.

(4)

Let superscrpt D stand for presence of defective trait and the symbol '-' stands for either presence D or absence of D.

I 1) AAXX 2) ADA-XY 3) AAXX 4) ADA-XY

II 1) to 4), 7), 8), 10), 12) Have ADA-XX 6), 9) and 11) AAXY 13) ADA-XY

III 1), 6) ADA-XY 2), 4) ADA-XX 3) AAXX 5) AAXY

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