given the following data on the rate of a reaction with and without inhibitor: W

Question

given the following data on the rate of a reaction with and without inhibitor:

Without inhibitor                          

With inhibitorKm = 0.02 mM                               Km = 0.01 mMVmax = 150                                    Vmax = 90What type of inhibition is consistent with these results?Uncompetitive

20. Given the following data on the rate of a reaction with and without inhibitor: Without inhibitor Km 0.02 mM Vmax= 150 With inhibitor Km = 0.01 mM Vmax = 90 What type of inhibition is consistent with these results? Uncompetitive

Explanation / Answer

For Competitive Inhibition

E + S ? ES ? P + E

+ I

EI + S ? No Reaction

For Uncompetitive Inhibition (Rare)

E + S ? ES ? P + E

+

I

?

            

         ESI (No Reaction)

Uncompetitive inhibition is possible.

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