What characteristics of the pathogen cause the rash that was observed? Endotoxin

Question

What characteristics of the pathogen cause the rash that was observed? Endotoxin inhibits the activation of platelets. Endotoxin triggers the release of Tumor necrosis factor (TNF) which damages capillaries. Exotoxin causes constriction of blood vessels leading to hypertension and leaky blood vessels Exotoxin Inhibits collagen synthesis that weaken blood vessel walls What is the mechanism of action of the drug? inhibits DNA synthesis inhibits the construction of mitotic microtubules. inhibits the construction of the cell wall inhibits synthesis of RNA

Explanation / Answer

3. ANS: B. Endotoxin triggers the release of Tumor necrosis factor which damages capillaries.

Explanation: Skin rashes caused by bacterial, viral, or fungal etiologies. Tumor necrosis factor is a cell signaling protein (cytokine) involved in systemic inflammation.

4. ANS: A. Inhibits DNA synthesis.

Explanation: There are several major targets of drug action: nucleic acids, specific metabolic and signaling enzymes, and microtubules. But several antimicrobials drugs targeting DNA replication, so it results to inhibits of DNA synthesis.

It is generally an action on the integrity or synthesis of DNA rather than of RNA that is presumed to cause cell death.

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