Coat color in mice is determined by two independently assorting but interacting

Question

Coat color in mice is determined by two independently assorting but interacting genes. The dominant allele at the Black locus (B) results in a black pigment being deposited in the fur; the recessive allele (b) leads to no pigment being made and an albino phenotype. The dominant allele (A) at the other locus, Agouti, results in a wild type or ‘agouti’ pigment pattern; the recessive allele (a) results in only the black pigment being seen. The bb phenotype is epistatic to the A- phenotype. In a testcross of Aa Bb mice X aa bb mice, what fraction of the progeny would have albino fur?

A. 1/4
B. 1/2
C. 3/16
D. 3/4
E. 9/16

Explanation / Answer

A. 1/4 =============== Aa Bb mice X aa bb mice gametes A B a b Ab a B a b ================= A B ab black Ab ab albino a B ab black a b ab black

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