Sickle cell anaemia: The selective forces that a population experiences can vary

Question

Sickle cell anaemia: The selective forces that a population experiences can vary by context, especially by geographic place. a) Explain in your own words how natural selection affects the evolution of haemoglobin in humans and how and why the selective pressures differ among human populations. b) For your answer to part a, which are examples of disruptive, stabilizing or directional selection? c) For human populations living in regions of the world without malaria, do you expect the HS allele to eventually go extinct? Explain. Sickle cell anaemia: The selective forces that a population experiences can vary by context, especially by geographic place. a) Explain in your own words how natural selection affects the evolution of haemoglobin in humans and how and why the selective pressures differ among human populations. b) For your answer to part a, which are examples of disruptive, stabilizing or directional selection? c) For human populations living in regions of the world without malaria, do you expect the HS allele to eventually go extinct? Explain. Sickle cell anaemia: The selective forces that a population experiences can vary by context, especially by geographic place. a) Explain in your own words how natural selection affects the evolution of haemoglobin in humans and how and why the selective pressures differ among human populations. b) For your answer to part a, which are examples of disruptive, stabilizing or directional selection? c) For human populations living in regions of the world without malaria, do you expect the HS allele to eventually go extinct? Explain.

Explanation / Answer

a.)The malaria parasites on population can exert selective pressure.this pressure has led to natural selection of erythrocytes cause sickle cell anaemia by carrying the sickle cell hemoglobin gean mutation is taken place.this is used in the place where malaria is the major problem in that places it helps to prevent it by giving some resistance to the disease.

It differs in human beings by giving the required dosage that a human being can bare and be healthy and this taken in larger amount even causes for dearth hence it differs.

b.)Directional selection:

In population genetics directional selection is a mode of natural selection in which by causing allele frequency shift over time in the direction of the phenotype that caused due to a extreme phenotype gets attracted to the other phenotype.

Disruptive selections:

This is also called as diversifying describe changes in population genetics in this extreme values for trait are favoured over intermediate values.

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