Imagine you have a patient who is clearly suffering from a deficiency of a parti

Question

Imagine you have a patient who is clearly suffering from a deficiency of a particular protein. Biochemical assays on blood and other tissues suggest the patient is producing considerable less of that protein that most people do, although production of all other proteins that were tested was normal. You check the DNA sequence of the gene that makes that protein, and everything seems to be in order. Because the production of other proteins is normal, you assume the patient's tRNAs, rRNAs and other genes' mRNAs are working properly. WHat other nucleic acids should you think about as a possible explanation for this?

Explanation / Answer

Here, the problem is related to the mRNA silencing process. The production of protein is affected by the mRNA expression, this will happen if the mRNA expression is low or the mRNA is silenced. In such cases, produced mRNAs are not translated into proteins resulting the deficiency of that particular protein

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