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In a typical cell, if the concentration of K+ in the ECF was increased from 5 mM

ID: 88682 • Letter: I

Question

In a typical cell, if the concentration of K+ in the ECF was increased from 5 mM to 7 mM. which of the following would occur? (Select all that apply, wrong answers earn negative points) a The membrane would depolarize. b The membrane would hyper polarize c The membrane potential would become more negative. d The membrane potential would become more positive. e The membrane potential would become less negative. f The membrane potential would become less positive. g The membrane potential would not change In a typical cell, if the concentration of K+ in the ECF was decreased from 5 mM to 3 mM. which of the following would occur? (Select all that apply, wrong answers earn negative points) a The membrane would depolarize. b The membrane would hyper polarize c The membrane potential would become more negative. d The membrane potential would become more positive. e The membrane potential would become less negative. f The membrane potential would become less positive. g The membrane potential would not change

Explanation / Answer

Extracellular fluid concentration changes inside or outside of the cell is largely depend on the ion concentration of the cell. Especially the K+ and Na+  ions makes the difference through the voltage-gated and voltage-insensitive ion channels.

If potassium ion concentration, present extracellular increases then the potassium gradient across the cell membrane decreases, this causes the resting membrane potential to become more positive. In the same way if extracellular potassium decreases, the resting membrane potential will be more negative.

1. Option a. The membrane would depolarize, and option d. is correct, as the membrane potential increases more,

If K+ concentration outside cells is higher because the resting potential shifts toward a higher equilibrium potential, therefore causing depolarization.

2. The potassium outflow hyperpolarizes the, as in case of neuron by a normal process. The movement of positively charged K+ ions to the outside of the cell moves the interior, here the channels like anchored voltage potential in the negative direction helps in hyperpolarization. Positively charged ions leaving cause the cell to become more negative, or hyperpolarized.

b. The membrane would hyperpolarize, and c. The membrane potential would become more negative.

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