Identify the true statements regarding the heme group of myoglobin and hemoglobi

Question

Identify the true statements regarding the heme group of myoglobin and hemoglobin. The iron in the heme group can form six bonds: The fifth is with an imidazole ring of a histidine and the sixth is with oxygen. The heme group is conjugated. The globin chains of myoglobin and hemoglobin prevent the oxidation of Fe2+ to Fe3+, which irreversibly binds oxygen. The T state of hemoglobin has lower affinity for O? than the R state because the Fe- Nporphyrin bonds are longer. A heme group contains four pyrrole rings, which are linked via methene (methine) bridges. The cooperativity of oxygen binding in hemoglobin arises from electronic interactions between heme groups. Hemoglobin contains four heme groups.

Explanation / Answer

1 is true

2 is true

3 is false

4 is true

5 is true

6 is true

7 is true

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