The dopamine transporter gene encodes a protein required to deliver dopamine alo

Question

The dopamine transporter gene encodes a protein required to deliver dopamine along the axon in pre-synaptic neurons towards the synapse. How might a variant allele of the dopamine transporter gene, which results in a transporter protein with reduced function, be involved in pre-disposing individuals to addictive behavior?

A. The dopamine transporter variant likely results in more stimulation being required to reach normal dopamine signaling levels

B. The dopamine transporter variant produces more dopamine in response to addictive behavior.

C. The dopamine transporter variant produces less dopamine in response to addictive behavior.

D. The dopamine transporter variant removes too much dopamine from the synapse

E. The dopamine transporter has low activity leading to high levels of dopamine signaling without the stimulation of addictive behavior

A. The dopamine transporter variant likely results in more stimulation being required to reach normal dopamine signaling levels

Explanation / Answer

For the addictive behavior, there are multiple possibilities that how dopamine is giving you pleasurable effect that sending signals to next neuron. If the dopamine molecules are not re absorbed in the axon by dopamine transporter. If the re absorbed molecules are lesser than the new molecules in the synapse.

The transporter with the reduced function can lead to addictive stage if the dopamine transporter variant likely to result in more stimulation being required to reach normal dopamine signaling levels. That is option A

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