Formation of Aspartame Which of the following will result in removal of a benzyl

ID: 907404 • Letter: F

Question

Formation of Aspartame

Which of the following will result in removal of a benzyl ether protecting group?

-Basic hydrolysis and decarbonylation

-Basic hydrolysis

-Decarbonylation

-Catalytic hydrogenolysis

-Basic hydrolysis, decarbonylation, and catalytic hydrogenolysis

Why does the phenylalanine methyl ester not require addition of a protecting group?

-It is not reactive enough

-The phenyl group serves as its own protecting group

None of the answers in this selection are correct

-The methyl ester serves as its own protecting group

-It is too reactive to need a protecting group

Catalytic hydrogenolysis

benzyl deprotection takes place with only hydrogenolasis in the presence of Pd/C

phenylalanine methyl ester

here free -NH2 group is still there with out protection

suppose if you are talking abput acid group then

The methyl ester serves as its own protecting group is correct answer

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