Which of the following correctly identifies the reactions catalyzed by aminoacyl

Question

Which of the following correctly identifies the reactions catalyzed by aminoacyl-tRNA synthetases?

Aminoacyl-ATP <> aminoacyl-AMP + PPi
Aminoacyl-AMP + tRNA <> aminoacyl-tRNA + AMP

Aminoacyl-AMP + ATP <> aminoacyl-ATP + AMP
Aminoacyl-ATP + tRNA <> aminoacyl-tRNA + ATP

Aminoacyl-ATP + tRNA <> aminoacyl-ATP-tRNA
Aminoacyl-ATP-tRNA <> aminoacyl-tRNA + AMP + PPi

Amino acid + ATP <> aminoacyl-AMP + PPi
Aminoacyl-AMP + tRNA <> aminoacyl-tRNA + AMP

Amino acid + tRNA + ATP <> aminoacyl-ADP + tRNA-AMP
Aminoacyl-ADP + tRNA-AMP <> aminoacyl-tRNA + ATP

Aminoacyl-ATP <> aminoacyl-AMP + PPi
Aminoacyl-AMP + tRNA <> aminoacyl-tRNA + AMP

Explanation / Answer

Ans.c)

Amino acid + ATP <> aminoacyl-AMP + PPi
Aminoacyl-AMP + tRNA <> aminoacyl-tRNA + AMP
Reason -

Amino acyl trna synthetase is an important enzyme for attachment of amino acids to corresponding trna. This is acheived by 2step process catalysed to attach amino acid . ATP is required for adding carboxylic and of AA to adenosine residue of trna

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