Where is the RNA polymerase II (RNAP) phosphorylated to activate RNAPII and to p

Question

Where is the RNA polymerase II (RNAP) phosphorylated to activate RNAPII and to promote transcription elongation? A on the N-terminal end of the largest RNA polymerase II subunit B on the central 20 amino acids of the largest RNA polymerase II subunit C on the 3' end of the largest RNA polymerase II subunit D on the 5' end of the largest RNA polymerase II subunit. E in the carboxyl-terminal domain (CTD) of the largest RNA polymerase II subunit A function or characteristic of initiator factors common to prokaryotes and eukaryotes. A Bring initiator tRNA to the P site on the small subunit B Bind uncharged tRNA to aminoacyl tRNA synthetases C Identify the start codon D Release stem loop structures E Catalyze peptide bond formation

Explanation / Answer

9. Answer :E

The C-terminal repeat domain (CTD), an extension appended to the C terminus of the largest subunit of RNA polymerase II, serves as a flexible binding scaffold for numerous nuclear factors. The phosphorylation patterns on the CTD repeats determines which factors get bound to RNA polymerase II.

10. Answer :B

Both Eukaryotic as well as Prokaryotic initiator factors bind the tRNA to aminoacyl tRNA synthetases.

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