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Why do you think that a \'frameshift\' mutation would generally be worse than a

ID: 9167 • Letter: W

Question

Why do you think that a 'frameshift' mutation would generally be worse than a 'base-pair substitution'?

A. Frameshift mutations result from a base being inserted or deleted, which causes all codons after the error to be different; base-pair substitutions only affect one codon, which alters one amino acid and may not change the protein's shape.

B. Frameshift mutations cause a change in multiple alleles, while base-pair substitutions affect only a single allele.

C. Frameshift mutations occur when entire chromosomes are lost or added, but base-pair subtitutions only affect single genes.

D. It wouldn't, frameshift mutations are usually good for the organism

Explanation / Answer

A. Frameshift mutations result from a base being inserted or deleted, which causes all codons after the error to be different; base-pair substitutions only affect one codon, which alters one amino acid and may not change the protein's shape.

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