A specific serine residue on a protein is the site of phosphorylation of an ATP-

Question

A specific serine residue on a protein is the site of phosphorylation of an ATP-dependent protein kinase. If the -oxygens of ATP were all 18O, how many labeled oxygens would the phosphorylated serine have (i) after it was phosphorylated and (ii) after a phosphatase catalyzed the hydrolysis of the phosphoryl group?

Question 8 options:

3 and 1

4 and 1

3 and 0

4 and 0

1 and 3

1 and 4

0 and 3

0 and 4

none of the other choices is correct

3 and 1

4 and 1

3 and 0

4 and 0

1 and 3

1 and 4

0 and 3

0 and 4

none of the other choices is correct

Explanation / Answer

The correct option is 3 and 1

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