Summateve Quiz tor Cha x Need Help With My x CO O www.macmi E.bsi. E3F55188 B00E

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Summateve Quiz tor Cha x Need Help With My x CO O www.macmi E.bsi. E3F55188 B00E 403C AS Apps Blackboard Queopard connection os wTEmal e Accudemia Login P Myub & Mastering D weswork:MAnita httpsuroglederalsek Done Summative Quiz for Chapter 14 which scenario supports Garrod's one gene, one enzyme hypothesis ormetabolic disease causation? o A neurological disease is due to a dominant allele in a single gene. O AToase, which catalyzes the first step in the pyrimidine biosynthetic a 12-subunit complex constructed of catalytic and regulatory dhains. pathway, is A blood disease is due to a recessive allele in one of two genes. Multiple genes contribute to the likelihood that a person will develop coronary heart disease. The disease pKU is due to the failure to produce a functional variant of an enzyme. 2. A strain of Neurospora is able to grow on minimal medium. when substance A is added to the medium, however, the strain cannot grow. Supplying a small amount of substance B has no effect on the strain, but it cannot reverse the effect of substance A. Supplying a small amount of substance C, by contrast, enables the strain to grow with substance A. Which of the following statements best explains these facts? Substance A is a toxin that the strain cannot break down, and substance cis an enzyme that breaks down substance A. Substance A is a mutagen, The strain has the capacity to produce substance C. Substance C is a mutagen. Substance A is a toxin that the strain cannot break down, and substance B is an enzyme that breaks down substance A. RIbozymes are RNA molecules that have enzymatic activity. This conflicts with the belief of early molecular biologists that each enzyme was encoded by one gene. the flow of information in gene expression goes in one direction. each enzyme is a polypeptide. O DNA information can be propagated into information in proteins, but information in proteins cannot be propagated into information in DNA. the flow of information in gene expression goes in both directions. which statement about RNA is false? Messenger RNAs are produced on ribosomes. Transfer RNA functions U RNAs are produced by transcription DNA codes for mRNA, tRNA, and rRNA in translation. Ribosomal RNA functions 32:00 Start B a

Explanation / Answer

Answers:

1. (e) The disease PKU is due to the failure to produce a functional variant of an enzyme

Explanation:

Phenylalanine hydroxylase is an enzyme which catalyzes the conversion of phenylalanine to tyrosine. In pateints with PKU, this enzyme is mutated (inactive) such that phenyalanine does not get catalyzed to tyrosine and the level of phenylalanine in the blood starts to increase. This results in damage of the nervous system and severe mental retardation. This supported Grrod's hypothesis that genes probably exerts its effects through enzymes.

2. (a) Substance A is a toxin that the strain cannot breakdown, and substance C is an enzyme that breaks down substance A.

3. (c) Each enzyme is a polypeptide

Explanation:

Initially it was thought that proteins are the only molecules capable of catalysis. Later it was discovered that ribozymes (catalytic RNAs) can also catalyze biochemical reactions.

4. (a) Messenger RNAs are produced on ribosomes

Explanation:

mRNAs are produced in the nucleus through the process of transcription from DNA and catalyzed by RNA polymerase.

(Since there are more than 1 question, the first 4 questions have been answered according to the rules of Chegg)

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