You have determined the primary sequence of a protein with the following charact

Question

You have determined the primary sequence of a protein with the following characteristics: a- Amino acids 1-10: (1) leucine. (2) Threonine. (3) Valine. (4) alanine. (5) glutamate. (6) arginine. (7) arginine. (8) leucine. (9) lysine. (10) lysine b- Amino acids 11-33 are primarily leucine, tryptophan, phenylalanine, and alanine c- Amino acids 34-60 are primarily glutamate, aspartate, alanine, and serine Based on the primary sequence, which of the following predictions is likely correct? This is an integral membrane protein with the amino terminus oriented to the outside of the plasma membrane and the carboxy terminus on the inside (in the cytosol). his is an integral membrane protein with the amino terminus and carboxy terminus on the same side of the membrane. From the sequence data it cannot be determined as to which side of the membrane the termini are on. This is an integral membrane protein with the amino terminus oriented to the inside of the plasma membrane (in the cytosol) and the carboxy terminus on the outside of the plasma membrane. This is a Type III integral membrane protein with the amino and carboxy termini in the interior of the hydrophobic bilayer. This is an integral membrane protein with both the amino and carboxy termini on the inside of the plasma membrane (in the cytosol).

Explanation / Answer

Since this protein contain both the amino side and carboxy terminal side those amino acids, which are hydrophilic in nature.

Due to the nature of hydrophilic, these amino acids lies in eigher side of the lipid bilayer and this side is inside of the plasma membrane ( in the cytosol).

So, the last answer is correct.

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