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Adenosine monophosphate (AMP) is a regulatory molecule in metabolic processes su

ID: 926975 • Letter: A

Question

Adenosine monophosphate (AMP) is a regulatory molecule in metabolic processes such as glycolysis and gluconeogenesis. For example, it stimulates the glycolytic enzyme phosphofructokinase, and therefore ATP production, and it inhibits the gluconeogenic enzyme fr 1,6-bisphosphatase. Adenylate kinase catalyzes the reversible reaction shown here 2+ Mg R ATP+ AMP ADP During periods of intense activity, when glycolysis is used in the generation of ATP, the reaction lies to the right, decreasing [ADP, generating ATP, and accumulating AMP. However, ATP is usually much greater than [ADP1, and [ADPI is greater than [AMP] Determine CAMP] when 5% of the ATP in a hypothetical cel is hydrolyzed to ADP In this cell, the initial concentration of ATP is 269 UM, and the total adenine nucleotide concentration (the concentration of ATP, ADP, and AMP) is 382 UM. The equilibrium constant K is 0.82 What is the concentration of AMP after 5% of the ATP is hydrolyzed to ADP? Number AMP

Explanation / Answer

Adenosine monophosphate (AMP) is a regulatory molecule in metabolic processes su

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