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Given the following schematic for a gene and its associated regulatory regions,

ID: 94394 • Letter: G

Question

Given the following schematic for a gene and its associated regulatory regions, answer the following questions A) Indicate where the RNA polymerase would bind this piece of DNA B) Indicate where the general transcription factor TFIID would bind this piece of DNA C) Circle what region or regions would provide cell type-specific expression D) Indicate what site would significantly increase gene expression E) Indicate what region or regions of this gene's coding sequence would NOT be expressed as amino acids

Explanation / Answer

A) RNA polymerase binds with the promoter sequences of DNA. Here, the promoter sequence is TATAAA.

B) The general transcription factor TFIID, binds to the promoter regions of DNA along with RNA polymerase. The promoter sequence here is TATAAA.

C) cell type specific expressions are produced by binding of transcription factors to either enhancer region or promoter region of DNA. They are usually adjacent to the genes they regulate. Sometimes they will bind directly to RNA polymerase. Here, it will bind to GCCCAATCT

D) An activator protein bound to the region upstream of enhancer region significantly increase gene expression. Here, it is GGGCGG region.

E) Introns are not expressed as amino acids.

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