12. Explain what happens to microfilaments within cells treated with cytochalasi

Question

12.

Explain what happens to microfilaments within cells treated with cytochalasin D and why existing actin polymers eventually depolymerize. Fill in the blanks in the explanation below using words from the selections below.

Cytochalsin D _______ of monomers at ______ of existing filaments. When the concentration of G-actin in the cytosol is _______ the critical concentration, the loss of monomers at __________ of existing filaments eventually results in their shortening.

** Selections: prevents addition; equal to; plus ends; facilitates loss; above; below; both minus and plus ends; minus ends

18.

What effect does VX, a typical but potent acetylcholinesterase inhibitor, have on muscle function? Fill in the blanks in the explanation below. A word bank of choices follows.

Because the removal of acetylcholine is inhibited, the muscle membrane at the nueromuscular junction will remain _____ for an abnormally long period, causing the muscles to remain in a ______ state. The prolonged ______ in turn would be propagated via the T tubule system to ________ . The result would be prolonged release of calcium, resulting in sarcomere _______ via the effects of calcium on ________.

***Selections: polarized; depolarized; polarization; depolarization; shortening; relaxing; contracted; the sarcoplasmic reticulum; the troponin system; myosin; Z lines

Explanation / Answer

Answer to the blanks are in following order

1. prevents addition, plus ends, equal to, minus ends.

2. polarised, contracted, polarisation, the sarcoplasmic reticulum, shortening, the troponin system.

Related Questions

Navigate

• Browse (All)
• Browse 1
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.