Protein kinase A is activated by which of the following small molecules A) Ca2^+

Question

Protein kinase A is activated by which of the following small molecules A) Ca2^+ B) cGMP. C) Diacylglycerol. D) Phosphatidylserine. E) cAMP. RTK signal amplification occurs in all of the following steps, except: A) Ras activation. B) Raf activation. C) MEK activation D) ERK activation E) Transcription factor phosphorylation. Gap junctions allow the movement of all but which of the following molecules between connected cells? A) Na^+ B) adenosine C) glucose-6-phosphate D) inositol-1, 4, 5-trisphosphate E) mRNA. The development of multidrug resistance in tumor cells has been associated with which class of transporters? A) P-type ATPases. B) ABC transporters C) Ion channels. D) Aquaporins. E) Gap junctions

Explanation / Answer

4) The answer is E) cAMP

Cyclic AMP is an important second messenger which forms when the membrane enzyme adenylyl cyclase is activated .An especially important protein activated by cyclic AMP is protein kinase A, which goes on the phosphorylate certain cellular proteins.

PKA (Protein Kinase-A) is a second messenger-dependent enzyme which has been implicated in a wide range of cellular processes, including transcription, metabolism, cell cycle progression and apoptosis.

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