Write out all the gametes produced by a person with the genotype I^AI^B. Write o

Question

Write out all the gametes produced by a person with the genotype I^AI^B. Write out the gametes produced by a person who is I^BI^B. (follow the nomenclature provided) What blood types are possible in the progeny if these two people were to have children? Cystic fibrosis (CF) is inherited as an autosomal recessive trait. Two carriers (heterozygotes) mate. A) What is the probability that their first child will have CF? B) Their first child is born and does have CF. The woman gets pregnant a second time. What is the probability that this second child will have the disease? Achondroplasia, a form of dwarfism, is inherited as an autosomal dominant. Two dwarfs, both of whom had one parent of normal height, marry and plan to have a child. A) What is the probability that their first child will be a dwarf? B) Their first child is born and is a dwarf. What is the probability that this child is heterozygous?

Explanation / Answer

2.The person with blood group AB will have following gametes-

Ia and Ib and the person who has blood group B will have following have Ib Ib and Ib Io

If these together produce progeny the probable blood groups of these would be-

Ia Ib

Blood group- AB and B.

Ia    Ib

RESULTS- IaIb- AB, Ib Ib- B Ia Io- A, Io Ib- B

Thus all the blood groups are possible in the progeny.

3.A. When both parents are carriers for a recessive disorder, each child has a 1 in 4 (25 percent) chance of inheriting the two changed gene copies. A child who inherits two changed gene copies will be “affected,” meaning the child has the disorder.

B.There is a 1 in 4 (25 percent) chance that the child will inherit both normal copies of a gene, and be unaffected and not a carrier.

Ib Ia Ib Ib Ib Ib Ia Ib Ib Ib

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