The incorporation of genome segments into progeny virions during influenza repli
ID: 95239 • Letter: T
Question
The incorporation of genome segments into progeny virions during influenza replication is non-random. The signals that mediate the packaging of vRNAs into virions are poorly understood but are thought to rely on sequences present in the vRNA. If the genome is divided into left arm non-coding, left arm coding, right arm non-coding and right arm coding, where is the most important sequence for selective packing. Refer to the constructs above and justify your reasoning. Define what virologists mean by the particle-to-pfu ratio and what values this ratio is expected to be? What are the implications of selective packaging on the particle-to-pfu ratio? What is the role of NA during influenza virus infection and spread? Draw a picture illustrating this role showing a wild type virus and a NA mutant virus (assuming this virus is viable).Explanation / Answer
the incorpation of dna is the corporating of dna in 100
under each dna nucleotides
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