Why are aldehydes more reactive towards nucleophiles than ketones? 2. It is not
ID: 962933 • Letter: W
Question
Why are aldehydes more reactive towards nucleophiles than ketones? 2. It is not advisable to prepare and store tollens' reagent in advance for test described in this experiment why? 3. oximes, phenyhyrazones, and semicarbazones all belong to a family compuonds known as imines what structural feature in these compounds makes this genralization valid? 4. Why does the nitrogen atom of the NH_2 (and not the nitrogen atrom of the NH) group of pheny|hydrazine act as the nucleophilic site in the formationn f phenyilhydrazons?Explanation / Answer
1)
Aldehydes are more reactive than ketones interms of nucleophilic substitution. The 2 main reasons are,
i. Steric effects:
In aldehydes the steric hinderence is less as it contains alkyl group and H, in ketones there are 2 alkyl groups, this makes the ketones more sterically hindered for incoming nucleophiles.
II. Electronic effects:
In ketone, the relative elctrophilicity of carbonyl carbon is decreased by 2 alkyl groups. But in case of aldehydes, there is only one alkyl group. Thus carbnyl carbon in aldehyde is more electrophilic than that of ketone.
Therefore, aldehyde is more reactive for incoming nucleophile.
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.