Assume that pyruvate labeled with 14 C at the carboxyl carbon (C1) is the only s

Question

Assume that pyruvate labeled with 14C at the carboxyl carbon (C1) is the only source that a bacterial culture has to make glucose via gluconeogenesis. Where will the label appear in the glucose that is produced?

C2 and C3 of glucose C1 and C4 of glucose C2 and C5 of glucose C3 and C6 of glucose C3 and C4 of glucose C2 and C6 of glucose C4 of glucose only C1 and C6 of glucose C3 and C5 of glucose C2 of glucose only C4 and C5 of glucose C1 and C3 of glucose C6 of glucose only C1 and C2 of glucose C5 and C6 of glucose C2 and C4 of glucose C3 of glucose only C1 of glucose only C5 of glucose only C4 and C6 of glucose C1 and C5 of glucose

Explanation / Answer

If C1 of puruvate is labelled with 14C isotope, the label in the final glucose would be at,

C1 and C6 of glucose

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