QUESTION 1 To ensure that RNA polymerase is only released after it has transcrib

Question

QUESTION 1

To ensure that RNA polymerase is only released after it has transcribed a gene to its end, termination is mechanistically linked to

5’ capping

excision of the lariat RNA

alternative splicing

3’ end formation

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QUESTION 2

For some pre-mRNAs, splicing is regulated by

RNA polymerase stalling

splicing enhancer sequences

localization of the pre-mRNA to subnuclear “speckles”

transcription termination

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QUESTION 3

The mechanism for nuclear pre-mRNA splicing is similar to the splicing mechanism of

Group I introns

Group II introns

Archael introns

nuclear tRNA introns

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QUESTION 4

One way to detect alternative splicing of a given gene is to compare:

the relative rate of transcription of the alternatively spliced gene with
another gene

the sequence of the alternatively spliced gene to that of another gene.

the size and frequency of different pre-mRNAs transcribed from this gene.

the size and sequence of mature mRNAs produced from this gene.

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QUESTION 5

Its gene is transcribed by RNA polymerase I.

There are about 50 genes in our genome encoding this type of molecule.

This molecule normally undergoes various covalent modifications.

It is normally composed of about 20 monomers.

Its gene transcript normally undergoes alternative splicing.

5’ capping

excision of the lariat RNA

alternative splicing

3’ end formation

Explanation / Answer

Answers

1. D. 3' end forming

2. D. Transcription termination

3. D. Nuclear tRNA introns

4. D. The size and sequence of mature mRNAs produced from this gene.

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