Which of the following are TRUE for steroid hormones in signaling but NOT TRUE f
ID: 966885 • Letter: W
Question
Which of the following are TRUE for steroid hormones in signaling but NOT TRUE for amino acid derivatives and polypeptides in signaling? i.e. What are the differences between steroids and other homones? A. They are a signal that must act indirectly. B. They almost always involve changing the expression of genes in our DNA. C. They almost always act on processes that take place over long periods of time. D. They are a signal that requires a receptor to work. E. They are a signal that can go through membranes.
Explanation / Answer
Steroid hormones because of their lipid nature can pass through the membranes. They involve in changing the gene expression in DNA. Their half-life is more compared to peptide hormones. So, they are important for processes that occur over long periods of time. So, for the steroid hormones the options (B), (C) and (E) are true.
Peptide hormones
Steroid hormones
Solubility
Water soluble
Lipid soluble
Ability to cross the cell membrane
Yes
No
Site of hormone receptor complex formation
Cell surface using receptors
Cytoplasm
Half life
Short
Long
Mediators
Secondary messengers like cAMP, cGMP, calcium, kinases
Receptor-hormone complex
Examples
Insulin, glucagon
Testosterone
Peptide hormones
Steroid hormones
Solubility
Water soluble
Lipid soluble
Ability to cross the cell membrane
Yes
No
Site of hormone receptor complex formation
Cell surface using receptors
Cytoplasm
Half life
Short
Long
Mediators
Secondary messengers like cAMP, cGMP, calcium, kinases
Receptor-hormone complex
Examples
Insulin, glucagon
Testosterone
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