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Which of the following are TRUE for steroid hormones in signaling but NOT TRUE f

ID: 966885 • Letter: W

Question

Which of the following are TRUE for steroid hormones in signaling but NOT TRUE for amino acid derivatives and polypeptides in signaling? i.e. What are the differences between steroids and other homones? A. They are a signal that must act indirectly. B. They almost always involve changing the expression of genes in our DNA. C. They almost always act on processes that take place over long periods of time. D. They are a signal that requires a receptor to work. E. They are a signal that can go through membranes.

Explanation / Answer

Steroid hormones because of their lipid nature can pass through the membranes. They involve in changing the gene expression in DNA. Their half-life is more compared to peptide hormones. So, they are important for processes that occur over long periods of time. So, for the steroid hormones the options (B), (C) and (E) are true.

Peptide hormones

Steroid hormones

Solubility

Water soluble

Lipid soluble

Ability to cross the cell membrane

Yes

No

Site of hormone receptor complex formation

Cell surface using receptors

Cytoplasm

Half life

Short

Long

Mediators

Secondary messengers like cAMP, cGMP, calcium, kinases

Receptor-hormone complex

Examples

Insulin, glucagon

Testosterone

Peptide hormones

Steroid hormones

Solubility

Water soluble

Lipid soluble

Ability to cross the cell membrane

Yes

No

Site of hormone receptor complex formation

Cell surface using receptors

Cytoplasm

Half life

Short

Long

Mediators

Secondary messengers like cAMP, cGMP, calcium, kinases

Receptor-hormone complex

Examples

Insulin, glucagon

Testosterone

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