Describe the three main stages involved in metastasis, including a description o

Question

Describe the three main stages involved in metastasis, including a description of the relevant cellular properties.

Describe the first stage involved in metastasis.

Select the two correct statements.

1) Cancer cells invade surrounding tissues and penetrate through the walls of lymphatic and blood vessels, thereby gaining access to the bloodstream.

Describe the three main stages involved in metastasis, including a description of the relevant cellular properties.

Describe the first stage involved in metastasis.

Select the two correct statements.

1) Cancer cells invade surrounding tissues and penetrate through the walls of lymphatic and blood vessels, thereby gaining access to the bloodstream.

2) The first step is facilitated by increased motility of cancer cells and increased size of the pores of surrounding tissues that allows the cells to pass by. 3) Cancer cells invade surrounding tissues and penetrate through the walls of lungs, thereby gaining access to the location of the most active receptors for adhesion as well as organ-specific conditions that influence cancer cell growth. 4) The first step is facilitated by decreased cell-cell adhesion, increased motility, and secretion of proteases that degrade the extracellular matrix and basal lamina. Cancer cells attach to air or carbon dioxide bubbles and pass with them through the walls of lymphatic and blood vessels, thereby gaining access to the bloodstream. The first step is facilitated by increased motility of cancer cells and increased adhesion to the air or carbon dioxide bubbles.

Explanation / Answer

Ans.) In general, metastasis refers to the term which deals with the extension of a cancer cell from one organ or in other parts of the body without direct connect. There are four different stages of metastasis; first, second, third and fourth These stages are the indication of large tumors that are full-grown and reached to several parts of the body.

• First Stage - In this stage, tumor cell is small in size and not grown into close by tissues. Not reached to the lymph nodes or other parts of the body. It is frequently called early-stage cancer.

• Second Stage II - In the following stage, the cancer cell or tumor cell is growing intensely into neighboring tissue.

• Third Stage – In the third stage, the cancer cell became larger and extended the nearby tissues and reached to the lymph nodes in the region.

• Fourth Stage – During this stage, the cancer cells have completely stretched to other organs or parts of the body and this stage also known advanced or metastatic cancer.

The two correct statement involved in first stage of metastasis are the 1 and 4.

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