A mutation arises in a bacterial cell that inserts three extra nucelotides into

Question

A mutation arises in a bacterial cell that inserts three extra nucelotides into the origin sequence of a plasmid. Assuming that replication of this plasmid is identical to the chromosome, select the statements below that describe a possible outcome. You may choose more than one. a) Replication may not be initiated b) The protein encoded by the origin would contain an extra amino acid c) DnaA may not bind effectively to the origin d) Translation of the origin may not occur e) Daughter cells may not each receive a copy of the plasmid

Explanation / Answer

Answer:

A mutation arises in a bacterial cell that inserts three extra nucleotides into the origin sequence of a plasmid. Assuming that replication of this plasmid is identical to the chromosome, select the statements below that describe a possible outcome. You may choose more than one:

a) Replication may not be initiated - Correct

b) The protein encoded by the origin would contain an extra amino acid

c) DnaA may not bind effectively to the origin - Correct

d) Translation of the origin may not occur

e) Daughter cells may not each receive a copy of the plasmid

The origin of replication sequence are called as OriC in a plasmid. Replication begins with active DnaA binding to 9-mer (9-bp) repeats upstream of oriC

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