You have taken a job at a metal plating plant, and some of the metals you work w

Question

You have taken a job at a metal plating plant, and some of the metals you work with contain arsenic as an impurity. The heated metals give off arsenic vapors, which create an average concentration of arsenic of 0.00002 mg/m^3 in the air in the workplace. What is your increased risk of cancer if you continue to work in this job for your entire carver? (Assume an adult male with a 70-y life expectancy, 45-y career, working 250 days/year. and with an inhalation rate of 10 m^3 day at work and 20 m^3/day overall.) There are about 220,000 workers in the United States in metal easting plants similar to the one in which you work. Mow many worker deaths above the background cancer rate would be expected due to their occupation? Suppose your workplace air also contains mercury in the air with an average concentration of 0.0001 mg/mg^3. Does this pose an acceptable risk from a carcinogenic and a non-carcinogenic standpoint? (Use the same parameters as in pan (a) for life expectancy, etc.)

Explanation / Answer

Arsenic is a metalloid, that is, considered to be a human carcinogen ranging from acute toxicities to development of malignancies, such as skin and lung cancer. Long term ingestion of inorganic arsenic has been associated with several human diseases. Recommended a threshold of 10g/L for inorganic arsenic concentration in drinking water.

The first inferences were made through observations of an increased frequency of skin cancer cases following treatment with Fowler’s solution (1% potassium arsenite), formerly used for a variety of skin and hematological disorders. Bowen’s disease, basal cell carcinoma (BCC)- and squamous cell carcinoma (SqCC) are the most common malignancies found in patients with long-term exposure to arsenic.

Skin cancer :-

Premalignant skin lesions are relatively early manifestations of arsenic toxicity and are often considered precursors to arsenic-induced skin BCC and SqCC tumors, prior signs of arsenicosis, such as keratosis and hyperpigmentation .

Lung Cancer

There exists a significant dose-response relationship between arsenic concentration in water and incidence of lung cancer and other malignancies for both men and women.

1. The risk assesed about 90% of people suffers with arsenic induced cancers due to constant inhalation of such metalloid may toxifies and kills

2. nearly 1,50,00 people may cause cancer due to poor immune response.

3. Mercury vapors in the mouth which spreads mercury to all points in the body, increased use of antibiotics, periodontal disease, inappropriate oral care, yeast and fungal overgrowth, and decreasing immune strength are all colliding and reinforcing each other in a downward spiral that leads to chronic diseases and cancer. Scientific studies have concluded that the amalgam is the source for more than two thirds of the mercury in our human population. On a daily basis each amalgam releases on the order of 10 micrograms of mercury into the body. This mercury either accumulates in the body or is excreted via urine and feces into our wastewater systems.

Its not acceptable risk, it site of dental oral cancers due to high intake of mercury along with daily food.

I hope this explanation helpful to you !

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